Research Technologist II
US-AZ-PHOENIX
commonspirit_careers
Req #: 476061
Type: Day
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Overview: Hello Humankindness: Join a Legacy of Healing at Saint Joseph's Hospital and Medical Center (SJHMC) Ready to make a real difference? Join SJHMC in Phoenix AZ., a 571-bed nonprofit founded by the Sisters of Mercy over 125 years ago. We're more than a hospital; we're a global destination for life-changing care, embracing patients with humankindness. Here, your calling will flourish. We're not just a workplace; we're a community dedicated to a mission of service. Leaders in Specialized Care: * Barrow Neurological Institute (BNI): A world-renowned center for groundbreaking neurological research and innovative treatments. * Norton Thoracic Institute (NTI): A national leader in advanced thoracic care with pioneering surgical techniques. * Level I Trauma Center: One of Arizona's busiest ERs, providing immediate, comprehensive care for critically injured patients 24/7. Why SJHMC? * Culture of Excellence & Well-being: We care for our people, fostering professional and personal growth. * Community & Collaboration: Be part of a network committed to global health and well-being. * Join a Legacy, Shape a Future: Over 20% of our patients travel internationally for our specialized care. This is an invitation to join a family of dedicated professionals at the forefront of medical innovation, united by the power of humankindness. Responsibilities: As a Research Tech, you will perform standard laboratory procedures with some independence, under the general supervision of a PI or Research Technician. Your contributions are vital for efficient lab operations. Every day you will execute experimental protocols, collect/record data, and maintain lab equipment. You may also perform complex procedures and provide guidance to students. To be successful in this role, you will possess a strong foundation in lab techniques, meticulous attention to detail, and work effectively independently and collaboratively. Reliability, safety adherence, and a willingness to learn are key. Other primary responsibilities include: * Receive process and manage biospecimens-including tumor tissue cerebrospinal fluid (CSF) and blood-in compliance with CLIA-regulated protocols * Isolate cell-free DNA from CSF and extract genomic DNA from tumor tissue and peripheral blood * Isolate circulating cells from CSF and perform tissue dissociation for downstream applications * Prepare single-cell RNA sequencing libraries using the 10x Genomics platform from tumor and CSF-derived cells * Generate DNA sequencing libraries from tumor tissue blood and cell-free DNA * Maintain rigorous accurate documentation of experimental workflows in accordance with established protocols and regulatory standards * Contribute to a collaborative research environment through participation in lab meetings seminars and journal clubs * Keeps accurate records of studies conducted with minimal supervision. * Performs basic data analysis and processing as required by senior laboratory personnel. * Creates, maintains, and updates lab's internal procedure manuals. The Ivy Brain Tumor Center is a pioneering non-profit clinical research program dedicated to developing transformative therapies for patients with aggressive brain tumors. As a global leader in early-phase neuro-oncology trials the Center hosts the largest portfolio of Phase 0 studies for brain tumors worldwide. Our multidisciplinary team integrates clinical care translational science and precision medicine to accelerate the identification and development of first-in-class therapies. We are seeking a highly motivated Research Tech II to join our translational neuro-oncology research team. This role is ideal for an individual with strong laboratory experience who is capable of independently executing complex experimental workflows. The successful candidate will play a key role in advancing innovative liquid biopsy platforms to study pharmacogenomic response tumor evolution and disease progression. Qualifications: Required * Bachelor's degree in biological sciences or a related field * Two (2) years prior experience in ar research, clinical, or other scientific environment * Prior laboratory research experience with demonstrated proficiency in cell culture molecular biology techniques (e.g. PCR qPCR) and/or sequencing library preparation * Strong analytical and problem-solving skills with the ability to learn and execute new techniques independently * Excellent attention to detail organization and time management * Strong written and verbal communication skills Preferred * Four (4) years of prior experience in a research, clinical, or other scientific environment * Background in cell biology neuroscience or oncology * Familiarity with CLIA-regulated workflows and liquid biopsy methodologies * Experience with single-cell RNA sequencing and next-generation sequencing platforms * Additional Information: Two to three letters of recommendation may be requested
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