Research Specialist, Antifungal Drug Development

				Overview:

The laboratory of Dr. Milena Kordalewska is seeking a dedicated and highly motivated Research Specialist, Antifungal Drug Development to contribute to our translational research programs focused on the development of novel antifungal drugs. Our lab is at the forefront of investigating emerging and drug-resistant fungal pathogens, and this position offers a unique opportunity to be part of a collaborative, mission-driven team. The successful candidate will play a crucial role in preclinical drug discovery initiatives with the ultimate goal of addressing a significant global health threat and improving patient outcomes.

The Research Specialist will be responsible for executing key laboratory experiments that form the foundation of our drug discovery pipeline. Primary responsibilities include:

* Conducting in vitro evaluations to determine the potency and spectrum of activity of novel antifungal compounds.
* Performing a variety of molecular biology assays to elucidate mechanisms of action and resistance.
* Assisting in conducting in vivo drug efficacy models in rodents to assess the therapeutic potential of lead candidates.

We are looking for a candidate with a strong foundation in microbiology and a keen interest in translational research. The following lab experience is highly desirable:

* Microbial cultures, particularly yeasts and filamentous fungi
* Drug susceptibility testing
* In vitro and in vivo biofilm models

The Center for Discovery and Innovation- CDI was established by Hackensack Meridian Health (HMH) as an academic basic and translational research enterprise to rapidly translate science innovation to the clinic and to improve outcomes for patients with cancer, infectious diseases, autoimmune disease and other acute and chronic diseases.  The CDI has grown rapidly since its origins in 2019, and now has 32 labs, 190 scientists and allied personnel supported by 60 NIH grants and more than 30 other grants and contracts. Areas of expertise include genomics, epigenetics, drug resistance, stem cell biology, drug discovery, diagnostics and biomarker development, and pharmacology.

Responsibilities:

A day in the life of a Research Specialist, Antifungal Drug Development , Center for Discovery and Innovation- CDI at Hackensack Meridian Health includes:

* Performs general laboratory functions including but not limited to equipment maintenance and restocking. 
* Assists in designing and performing experiments and data analysis. 
* Maintains accurate notes and records of all research performed. 
* Performs data collection and interpretation of results. 
* Creates reports from analysis of initial observations and conclusions. 
* Establishes experimental protocols, design and documentation. 
* Responsible for the day-to-day operations of the lab. 
* Recommends changes to the lab practices and procedures. 
* Uses necessary equipment to perform studies. 
* Maintains lab space. 
* Learns about and shares with laboratory members the latest advances in laboratory techniques being used. 
* Communicates issues to the Principal Investigator, Laboratory Manager or Department Chair. 
* Other duties and/or projects as assigned. 
* Adheres to HMH Organizational competencies and standards of behavior.

Qualifications:

Education, Knowledge, Skills and Abilities Required: 

* Bachelor's degree or equivalent training. 
* Minimum of 1 or more years of experience. 
* Ability to work independently and have a strong work ethic. 
* Ability to work well with others in a team environment. 
* Flexible in work schedule. Must be available to occasionally come to the laboratory on a weekend day or stay late for a given experiment. 
* Lab specific technical skills. 
* Excellent written and verbal communication skills. 
* Proficient computer skills that include but are not limited to Microsoft Office and/or Google Suite platforms. 

Education, Knowledge, Skills and Abilities Preferred:

* B.Sc. or Master's degree. 
* Experience working in a BSL2/BSL3 lab facility. 
* Experience with small animal handling. 
* Other lab specific. 

If you feel that the above description speaks directly to your strengths and capabilities, then please apply today!
			

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Hackensack Meridian Health